INTERSTITIAL PERFUSION CULTURE WITH SPECIFIC SOLUBLE FACTORS INHIBITS TYPE I COLLAGEN PRODUCTION FROM HUMAN OSTEOARTHRITIC CHONDROCYTES IN CLINICAL-GRADE COLLAGEN SPONGES.

Interstitial Perfusion Culture with Specific Soluble Factors Inhibits Type I Collagen Production from Human Osteoarthritic Chondrocytes in Clinical-Grade Collagen Sponges.

Articular cartilage has poor healing ability and cartilage injuries often evolve omni logic plus to osteoarthritis.Cell-based strategies aiming to engineer cartilaginous tissue through the combination of biocompatible scaffolds and articular chondrocytes represent an alternative to standard surgical techniques.In this context, perfusion bioreactors

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Synthesis and biological evaluation of the progenitor of a new class of cephalosporin analogues, with a particular focus on structure-based computational analysis.

We funko dab rig present the synthesis and biological evaluation of the prototype of a new class of cephalosporins, containing an additional isolated beta lactam ring with two phenyl substituents.This new compound is effective against Gram positive microorganisms, with a potency similar to that of ceftriaxone, a cephalosporin widely used in clinics

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Tungiasis infestation in Tanzania

Tungiasis is caused by the jigger flea Tunga penetrans.We describe a case of severe infestation from Kigoma region, Western Tanzania.A 19-year-old male with epilepsy and mental disability presented with ulcerated and inflamed toes.Clinical examination revealed the presence of approximately 810 embedded jigger fleas on the feet, and opi the color th

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